Effect of aqueous extract of Agaricus bispporus on lipid profile of female albino mice treated with peroxide

  • Dina khudhair HusseinAli Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq

Abstract

Agaricus bisporus is cultivated edible mushroom . This study is made to evaluate the  activity of A. bisporus extract  on  lipid profile in mice treated with peroxide.  40 females albino mice were chosen and  divided into 4 groups (ten mice per each group). The first group was treated with normal saline as a control, the second group received 2ml/kg body weight of peroxide , While the third set received 2ml/kg body weight of peroxide plus 25 mg/ml  A bisporus .Besides, the last fourth group received 25 mg/ml  of A. bisporus. The Results have showed a significant increase (p? 0.05) in cholesterol(CH) in group 2 (250.01 1.05)and group3 (204.251.80), while there was no significant decrease in CH  level of group 4(170.012.01) as compared with control group(184.00 1.02). As well, there was a significant increase in Low Density Lipoprotein (LDL) in group 2 (159.230.9) and group 3 (158.322.00), while there was a significant decrease (110.951.3) in the level of this parameter in group 4 as compared with the control group(115.982.2). Moreover,  there was a significant differences in the levels High Density Lipoprotein ( HDL) ,Very Low Density Lipoprotein (VLDL)  Triglyceride and in all treated groups compared with the control group.

Published
Dec 25, 2018
How to Cite
HUSSEINALI, Dina khudhair. Effect of aqueous extract of Agaricus bispporus on lipid profile of female albino mice treated with peroxide. Iraqi Journal of Science, [S.l.], p. 2168-2172, dec. 2018. ISSN 2312-1637. Available at: <http://scbaghdad.edu.iq/eijs/index.php/eijs/article/view/558>. Date accessed: 24 june 2019.
Section
Biology